Product pipeline

Through our pipeline, we are researching life-changing medicines that make birth, life and living possible.

Title description	Indication	Phase 1	Phase 2	Phase 3	Phase 4
Evalute the effect of carbetocin on the QT/QTc interval in healthy subjects (TQT phase)	Postpartum haemorrhage	✓
ADAM: Assessment of follitropin delta efficacy and safety for treatment of men with idiopathic infertility	Idiopathic male infertility		✓
Rekovelle India: Multicentre trial in India comparing the efficacy and safety of follitropin delta with follitropin alfa in controlled ovarian stimulation in women undergoing ART	Infertility			✓
BEYOND (phase completed): Compare the efficacy and safety of individualised follitropin delta dosing, using a long GnRH agonist protocol and GnRH antagonist protocol in women undergoing controlled ovarian stimulation	Infertility			✓
ADAPT: Assessment of conventional dosing in women undergoing ART with follitropin delta treatment	Infertility				✓

Title description	Indication	Phase 3	Phase 4
Evaluate the safety and efficacy of Adstiladrin administered intravesically to Japanese subjects with high grade BCG-unresponsive non-muscle invasive bladder cancer	High-risk non- muscle invasive bladder cancer (HR NMIBC)	✓
Adstiladrin early utilisation and outcomes in the real-world setting in the U.S. Non-interventional real-world study	High-risk non- muscle invasive bladder cancer (HR NMIBC)		✓
Post-authorisation observational cohort safety study of hyponatraemia and cardiovascular and thromboembolic events in nocturia patients treated with Nocdurna	Nocturia		✓
Non-interventional, observational PAP data-based study to investigate the post-marketing safety by intensive monitoring of Firmagon in Chinese patients (phase completed)	Prostate cancer		✓

Title description	Indication	Phase 1	Phase 4
Explore the safety and clinical effectiveness of Rebyota administered by colonoscopy to adults with recurrent Clostridioides difficile infection	Recurrent Clostridioides difficile infection	✓
Pragmatic randomised controlled study of mesalazine and budesonide to assess the effectiveness of two patient management strategies in mild to moderate ulcerative colitis	Ulcerative colitis	✓
Evaluate the safety and tolerability of Rebyota (microbiota suspension) in subjects with recurrent Clostridioides difficile infection	Recurrent Clostridioides difficile infection		✓
Observational study of Rebyota for the prevention of recurrence of Clostridioides difficile infection in adult patients	Recurrent Clostridioides difficile infection		✓
Non-interventional study to describe the safety of Picolax (phase completed)	Bowel preparation		✓