Meet Laurent Derré, Ferring Innovation Grant recipient
Title: Research Associate, PhD, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland
Research Project: Understanding Siglec-related immunity in bladder cancer.
Our project will explore whether immune regulators may be involved in bladder cancer recurrence and/or treatment failure.
What motivated you to research this area? I have always been fascinated by the way tumours can hijack regulatory mechanisms. I want to better understand immune regulatory mechanisms involved in bladder cancer and its treatment to optimise immunotherapy against bladder cancer.
What do you hope to achieve through your grant? Bladder cancer is the ninth most common cancer in the world. We ultimately want this research to help the estimated 430,000 people diagnosed each year.
Most challenging part of your project? We are focusing on a family of inhibitory receptors called Siglecs, which are able to interact with sugars (Sialic acids) linked to other cells’ surface proteins. The fact that Siglecs recognise sugars, and not proteins like almost all the regulatory receptors, adds an extra level of complexity to the project.
How would you describe yourself in 3 words? Curious, enthusiastic, discreet.
Interesting fact about yourself? I am a big Star Wars fan!
Visit www.ferring-research.com/ferring-grants to learn more about the Ferring Innovation Grants Program.